Countries in conflict: Enabling access to medicines during times of unrest

Consistency of supply is critical for any Managed Access Program (MAP). However, even the most thoroughly planned programs can be disrupted. Disruption can appear in all shapes and sizes; force majeure events as wide as global pandemics, as isolated as airport fires and as narrow as regional flooding all pose risks for continuity of care. Political landscapes are ever evolving, and although some instability is predictable, unforeseen events and circumstances can put access routes in jeopardy. Conflict, whether cross-border or internal, has significant impact on global supply chains, putting supply for both established and newly launched MAPs at risk.

At this year’s Clinigen Insights Conference, Jenny Pearce, VP Client Delivery and Hannah Jones, Senior Legal Counsel, explored the realities of operating in these challenging environments, and shared how to design contingency plans and robust solutions to ensure vital medicines reach patients despite instability in a region.

Program considerations

Conflict affects every part of the supply chain. Whether clients are initiating an Early Access Program, continuing ongoing supply, or healthcare professionals are striving to maintain treatment for their patients, disruption is felt by all.

Sanctions, intrinsically tied to conflict, also introduce additional complexity. Financial, economic, and trade restrictions put pressure on supply chains, which can lead to delays and interruptions. Blocked borders, held shipments and banking restrictions are real-life consequences to increased sanctions, which may directly affect patients. To overcome these challenges, robust processes are critical to ensure compliant and consistent supply.

Coping with unpredictability

Clinigen has extensive experience enabling access in hard-to-reach regions. Our global network and expertise help guide clients toward the most suitable solutions and address associated operational challenges.

Close communication with logistics partners and suppliers allows us to pivot quickly. Whether that means utilising new warehousing models or transportation solutions, rerouting through alternative countries or adjusting packaging controls. Our goal is to ensure access to patients in need of life-changing medicines.

Building supply chain robustness

To provide access to medicines effectively in countries facing disruption, it is essential to establish a robust supply chain capable of withstanding unpredictability. Drawing on real-world experience, Clinigen has established a framework that includes:

1. Network Strategy:

o Multiple and validated shipping lanes
o Preference for in-country presence
o Dual sourcing and contingency routing
o Import/export hub flexibility

2. Operational Excellence:

o End-to-end tracking, including GPS
o Next Flight Out (NFO) capabilities
o Qualified shippers and maintenance processes
o Detailed Customer Service and Key Account Management

3. Risk & Governance:

o Fully defined business continuity plans
o KPIs, weekly business review meetings, and continuous improvement projects
o Strong internal stakeholder infrastructure to maximise client and customer responsiveness

Key takeaways

When working in countries affected by conflict, success depends on strong communication and collaboration, combined with the ability to adapt at short notice. The global landscape can change quickly, and unforeseen events can cause huge disruption, making a resilient network, experienced partners, and robust processes essential. Above all, patients must remain at the forefront of every decision and every solution.

If you're facing unforeseen disruption, we're here to help. Get in touch to discuss tailored solutions and ensure vital medicines reach those in need.